Papers

Please browse here to find research papers published by our clients utilising Ozgene mice.

2010

1. A comparative study of Lrrk2 function in primary neuronal cultures. (KO conditional)
JC Dächsel; B Behrouz; M Yue; JE Beevers; HL Melrose; MJ Farrer
Parkinsonism & related disorders, 2010 Dec;16(10):650-5. Epub 2010 Sep 17.
Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
2. Discrete change in volatile anesthetic sensitivity in mice with inactivated tandem pore potassium ion channel TRESK. (KO non-conditional)
YJ Chae; J Zhang; P Au; M Sabbadini; GX Xie; CS Yost
Anesthesiology, 2010 Dec;113(6):1326-37
Department of Anesthesia and Pain Medicine, Ajou University Medical Center, Suwon, Korea.
3. Whole-body deletion of AMPK 2 reduces muscle AMPK and exercise capacity. (KO conditional)
Campbell, DJ; Chen, ZP; Dzamko, NL; Galic, S; Hewitt, K; Honeyman, J; Jorgensen, SB; Kemp, BE.; Koentgen, F; Koopman, R; Lynch, GS; Naim, T; O'Neill, HM; Schertzer, JD; Scott, J; Steinberg, GR; Vandenderen, BJ; Watt, MJ
J Biol Chem, 2010 Nov 26;285(48):37198-209. Epub 2010 Sep
Department of Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.
4. microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. (KO conditional)
Cambronne, XA; Goodman, RH.; Leighton, BH; Lioy, DT; Luikart, BW; Magill, ST; Mandel, G; Westbrook, GL
PNAS, 2010 Nov 23;107(47):20382-7. Epub 2010 No
Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
5. The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas. (KO conditional)
Pasquale, EB.; Roselli, S; Vervoort, V; Wallez, Y; Wang, L
Cell Signal, 2010 Nov;22(11):1745-52. Epub 2010 Jul
Sanford-Burnham Medical Research Institute, 10901 N Torrey Pines Rd, La Jolla, CA 92037, USA.
6. Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells. (KI non-conditional)
Cantrell, DA.; Emslie, E; Feijoo-Carnero, C; Matthews, SA; Navarro, MN; Sinclair, LV
Biochem J, 2010 Nov 15;432(1):153-63. doi: 10.1042/BJ20101188.
Ninewells Hospital, University of Dundee, Scotland, UK.
7. Hormonally regulated follicle differentiation and luteinization in the mouse is associated with hypoxia inducible factor activity. (Tg lentiviral)
KK Tam; DL Russell; DJ Peet; CP Bracken; RJ Rodgers; JG Thompson; KL Kind
Molecular and cellular endocrinology, 2010 Oct 7;327(1-2):47-55. Epub 2010 Jun 25.
The Robinson Institute, Research Centre for Reproductive Health, The University of Adelaide, South Australia, Australia.
8. The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. (KO conditional)
Coré, N; Cremer, H; Pasquale, EB.; Vervoort, V; Wallez, Y; Wang, L
J Neurosci, 2010 Sep 29;30(39):13201
Sanford-Burnham Medical Research Institute, La Jolla, California 92037, USA.
9. Regional neural tube closure defined by the Grainy head-like transcription factors. (KO/KI)
Y Rifat; V Parekh; T Wilanowski; NR Hislop; A Auden; SB Ting; JM Cunningham; SM Jane
Developmental biology, 2010 Sep 15;345(2):237-45.
Melbourne Health Research Directorate, c/o Royal Melbourne Hospital Post Office, Parkville, VIC 3050, Australia.
10. Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation. (KI non-conditional)
Bey, AL; Bugge, TH.; Chavakis, T; Choi, EY; Connolly, BM; Currie, BM; Gårdsvoll, H; Leppla, SH; Liu, S; Molinolo, A; Ploug, M
Blood, 2010 Sep 2;116(9):1593-603. Epub 2010 May
Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
11. In vivo studies of mutant fibrillin-1 microfibrils. (KI conditional)
Carlberg, VM; Carlson, EJ; Charbonneau, NL; Keene, DR; Manalo, EC; Ramirez, F; Sakai, LY.; Sengle, G; Tufa, S
J Biol Chem, 2010 Aug 6;285(32):24943-55. Epub 2010 Ju
Shriners Hospital for Children, Oregon Health & Science University, Portland, Oregon 97239, USA.
12. PNPASE regulates RNA import into mitochondria. (KO conditional)
Allen, EL; Chen, HW; Fan, KC; French, SW; Hong, JS; Koehler, CM; Lightowlers, RN; McCaffery, JM; Morse, HC 3rd; Oktay, Y; Smith, GM; Teitell, MA.; Wang, G; Zhang, J
Cell, 2010 Aug 6;142(3):456
Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095, USA.
13. Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. (KO conditional)
Beck, H; Berkovic, SF; Cromer, BA; Davies, PJ; Hill, EL; Horstmann, MT; Leaw, BT; Lerche, H; Mitchell, S; Petrou, S.; Reid, CA; Richards, KL; Royeck, M; Scaf, BB; Wimmer, VC; Xu, R
J Clin Invest, 2010 Aug 2;120(8):2661-71. doi: 10.1172/JCI42219. Epub 2010 Jul
Florey Neuroscience Institutes, The University of Melbourne, Parkville, Victoria, Australia.
14. S100A4 regulates macrophage chemotaxis (KO conditional)
Li ZH; Dulyaninova NG; House RP; Almo SC; Bresnick AR
Mol Biol Cell, 2010 Aug 1;21(15):2598-610. Epub 2010 Jun 2.
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
15. AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. (KI non-conditional)
Bendor, J; Brandstetter, M; Flajolet, M; Greengard, P.; Hemmings, HC Jr; Lizardi-Ortiz, JE; Sulzer, D; Westphalen, RI
EMBO J, 2010 Aug 18;29(16):2813-26. Epub 2010 Jul
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.
16. Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice. (Tg pronuclear injection)
Aird, WC; Ballermann, BJ; Jahroudi, N.; Kulak, S; Liu, J; Nassiri, M; Uwiera, RR
Arterioscler Thromb Vasc Biol, 2010 Jul;30(7):1423-9. Epub 2010 Apr
University of Alberta, Edmonton, AL, Canada.
17. Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene, BORIS (KO/KI)
Abdullaev, Z; Kosaka-Suzuki, N; Lobanenkov, V.; Loukinov, D; Morse, HC 3rd; Pack, S; Pugacheva, E; Shin, DM; Suzuki, T; Yoon, J
Journal Mol Cell Biol, 2010 May;30(10):2473-84. Epub 2010 Mar
Laboratory of Immunopathology, National Institutes of Allergy and Infectious Diseases, NIH, Rockville, MD 20852, USA.
18. c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway. (KI non-conditional)
Dagger, SA; Jansen, ES; Koentgen, F; Langdon, WY; Scott, CL; Steer, JH; Thien, CB
J Biol Chem, 2010 Apr 2;285(14):10969-81. Epub 2010 Fe
School of Pathology and Laboratory Medicine, University of Western Australia, Crawley 6009,Western Australia.
19. Expression of helios, an ikaros transcription factor family member, differentiates thymic-derived from peripherally induced foxp3+ T regulatory cells. (KO conditional)
Belkaid, Y; Korty, PE; Murray, PE; Shevach, EM.; Thornton, AM; Tran, DQ; Wohlfert, EA
J Immunol, 2010 Apr 1;184(7):3433-41. Epub 2010 Feb
Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
20. Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia. (Not categorised)
De, Silva TM; Diep, H; Drummond, GR; Judkins, CP; Miller, AA; Sobey, CG.
Stroke, 2010 Apr;41(4):784-9. Epub 2010 Feb
Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
21. Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance. (KO conditional)
Chan, CB; Jun, JY; Jung, DY; Kim, JK; Liu, X; Luo, HR; Ye, K.
Diabetes, 2010 Apr;59(4):883-93. Epub 2010 Jan
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
22. PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development. (KO conditional)
Chan, CB; Dillehay, DL; Ensslin, MA; Liu, X; Ormandy, CJ; Serra, R; Sohn, P; Ye, K.
EMBO J, 2010 Mar 3;29(5):956-68. Epub 2010 Jan
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
23. Germline deletion of AMP-activated protein kinase subunits reduces bone mass without altering osteoclast differentiation or function. (KO conditional)
Gillespie, MT; Kemp, BE; McGregor, NE; Poulton, IJ; Quinn, JM; Saleh, H; Scott, JW; Sims, NA; Tam, S; van, Denderen BJ.
FASEB J, 2010 Jan;24(1):275-85. Epub 2009 Se
Prince Henry's Institute, Monash Medical Centre, Clayton, Australia.
24. Death-associated protein kinase-mediated cell death modulated by interaction with DANGER (KO conditional)
Ahmad, AS; Doré, S; Hester, L; Kang, BN; Patterson, RL; Saleem, S; Snyder, SH.
J Neuroscience, 2010 Jan 6;30(1):9
Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
25. Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. (KO conditional)
Cooney, GJ; Furler, SM; Hegarty, BD; Hoehn, KL; Hoy, AJ; James, DE; Joshi, H; Kraegen, EW; Larance, M; Leslie, SJ; Phua, Y; Pickford, R; Preston, E; Swarbrick, MM; Turner, N; Wilks, D
Cell Metab, 2010 Jan;11(1):7
Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
26. Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice (Not categorised)
Broughton, BR; Diep, H; Drummond, GR.; Dusting, GJ; Hooker, EU; Judkins, CP; Mast, AE; Miller, AA; Selemidis, S; Sobey, CG
Am J Physiol Heart Circ Physiol, 2010 Jan;298(1):H24-32. Epub 2009 Oct
Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
27. Engineering the mouse genome to model human disease for drug discovery. (Not categorised)
Koentgen, F; Naf, D.; Suess, G
Methods Mol Biol, 2010;602:55
Ozgene Pty Ltd, Bentley, WA, Australia.
28. Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory. (KO conditional)
Albiston, AL; Burns, P; Chai, SY.; Daswani, D; Diwakarla, S; Fernando, RN; Ng, L; Pham, V; Yeatman, HR
Neurobiol Learn Mem, 2010 Jan;93(1):19-30. Epub 2009 Au
University of Melbourne, Parkville, Victoria 3010, Australia.
29. Toll-like-receptor-4 Inhibits Enterocyte Proliferation via Impaired beta-catenin Signaling in Necrotizing Enterocolitis. (KO conditional)
Branca, M; Grant, ZS; Gribar, SC; Hackam, DJ.; Ma, C; Prindle, T Jr; Richardson, WM; Russo, A; Shapiro, RA; Shi, XH; Sodhi, CP
Gastroenterology, 2010 Jan;138(1):185-96. Epub 2009 Sep
Division of Pediatric Surgery, Department of Surgery, Children's Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA.

29 Publication(s)