2024
Mucosal Immunol. 2024 Feb 7:S1933-0219(24)00007-2. doi: 10.1016/j.mucimm.2024.02.003.
A Trefoil factor 3-Lingo2 axis restrains proliferative expansion of type-1 T helper cells during GI nematode infection
Service type: Knock-in mice
2023
NPJ Parkinsons Dis. 2023 Dec 18;9(1):167. doi: 10.1038/s41531-023-00609-7.
Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice
Service type: Knock-in mice
2023
EMBO Rep. 2023 Nov 14:e57972. doi: 10.15252/embr.202357972. Online ahead of print.
MAPL loss dysregulates bile and liver metabolism in mice
Service type: Knock-in mice
2023
Am J Physiol Gastrointest Liver Physiol. 2023 Nov 14. doi: 10.1152/ajpgi.00140.2023. Online ahead of print.
Defining a timeline of colon pathologies after keratin 8 loss: Rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation
Service type: Knockout mice
2023
Am J Hum Genet. 2023 Nov 3:S0002-9297(23)00358-0. doi: 10.1016/j.ajhg.2023.10.005. Online ahead of print.
Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need
Service type: Knock-in mice
2023
Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2306761120. doi: 10.1073/pnas.2306761120. Epub 2023 Sep 27.
Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation
Service type: Knockout mice
2023
Diabetes. 2023 Sep 12:db230035. doi: 10.2337/db23-0035. Online ahead of print.
Dual Tracer Test to measure tissue-specific insulin action in individual mice identifies in vivo insulin resistance without fasting hyperinsulinemia
Service type: Knock-in mice
2023
Nat Commun. 2023 Aug 19;14(1):5053. doi: 10.1038/s41467-023-40681-4.
CD98hc is a target for brain delivery of biotherapeutics
Service type: Knock-in mice
2023
Immunity. 2023 Aug 8;56(8):1778-1793.e10. doi: 10.1016/j.immuni.2023.06.020. Epub 2023 Jul 17.
Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks
Service type: Knock-in mice
2023
JCI Insight. 2023 Jul 10;8(13):e134685. doi: 10.1172/jci.insight.134685.
Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors
Service type: Knock-in mice