• goGermline the first time

    goGermlinethe first time

    Generate germline mice faster

    goGermline is a revolutionary new technology to generate knockout and knock-in mouse models. Our fastest project has been completed in 20 weeks.

  • goGermline more efficiently

    goGermlinemore efficiently

    All offspring are derived from ES cells

    Ideal for compromised ES cells that normally would not give germline transmission, including repository ES cell clones.

  • goGermline is the winner

    goGermlineis the winner

    of the inaugural ISTT 3Rs prize

    Greatly improves animal welfare by addressing the 3Rs: replace, reduce, refine. We can guarantee that only ES cell derived animals are produced at chimera breeding.

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Welcome to Ozgene

Ozgene is an Australian company that generates customised genetically modified mice for drug validation and medical research trials worldwide. Using Lean Management, we are able to efficiently and consistently provide our clients with high quality mouse models so that you too, can advance humanity and inspire curiosity.

Did you know that Ozgene’s founders, Dr Frank Koentgen and Dr Gabi Suess, were the first to successfully produce a C57BL/6 knockout mouse in 1993? Ozgene was founded in 1999 based on that initial accomplishment. Since then, we have established a long history of continued success. Today Ozgene is one of the leading companies providing genetically customised mice for researchers around the world.

Ozgene mice can be found all over the globe. This is evidenced by the distribution of published papers that reference mice created by Ozgene. We currently have over 400 papers published, more than any other competing company. We would love to add your paper to the list, so if you have a project in mind, please see our current services below and contact us for a confidential, obligation free assessment.

What's New?

  • Significant Science Immunology paper >

    Congrats on an outstanding immuno-oncology paper to Vicky Boussiotis and her team at the Beth Israel Deaconess Medical Center! The paper that also features Ozgene mice has been downloaded over 26,000 times since 3 January.

    Read paper

  • 2020 start with 20wk project >

    Great start to 2020 - first conditional KO project of the year completed to F1 mice in 20 weeks! What a great way to continue our 20th year!

    See timelines

  • ISTT2019 goGermline poster >

    Did you see the latest data on goGermline by Ozgene® expediting time to first experimental cohorts at the ISTT2019 meeting in Kobe?

    Download poster

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Our Services

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The Big History Project

Have you heard of the Big History Project? No? Well, prepare to be enlightened then. Recently, I was introduced to this project and have since been fascinated with it. For this blog post, I’d like to introduce you all to the Big History Project. Then, once you’ve had a chance to explore it further on your own, I’ll follow up next month with how I see it applying to Ozgene.



So what is the Big History Project? Well, to summarize, it is essentially the story of us (humans). It brings together our past, present and our future; bringing everything together in its increasing complexity. It is multi-disciplinary and began with a desire to go beyond specialized fields of study (like biology, physics, chemistry, religion, etc.) to grasp history as a whole. The current target audience of the Big History Project is high school students, but it is designed for anyone interested in finding the answers to the big questions about the history of the Universe. It is a joint project that brings together teachers, scholars, scientists and others.

Some of the key concepts behind the Big History Project, according to one of the founders, David Christians, are:

  • We are the first species in 4 billion years in which information accumulates across generations (with increasing complexity), through the cultural mechanism, not through the genetic mechanism.
  • The cultural mechanism, of course, is orders of magnitude faster than the genetic mechanism.
  • Environments to control and manage the energy flows they need to survive—biologists call it metabolism—or to constantly adjust—homeostasis—then we know that most living organisms have a limited repertoire.
  • When a new species appears, its numbers will increase until it's using the energy that its particular metabolic repertoire allows it to fill.
  • If you think of languages as communicating with a certain level of efficiency, then information theory comes into this.
  • There's rich material in the information theory, and I wouldn't pretend to understand it in detail.
  • You can measure the efficiency of information systems. So much information is conveyed with a certain degree of precision or not.
  • I can say four syllables "Pink Elephant," and suddenly an image will pop into someone's brain of something that's never existed and never has.
  • Symbolic language allows us to talk about things that are not here. It vastly increases the range of what we can communicate.
  • Once you cross that, then you are in new territory.

The Big History Project is currently being taught in 100 high schools across Australia and in over 400 more in the United States. David Christians has also taught the subject in other countries as well. Since 2010, Bill Gates has supported the website for the Big History Project. It is free for everyone. I encourage you to check it out, to think about it and to even begin to apply it. Next month, I’ll divulge into how I have done exactly that using Ozgene and its evolution.

- Frank, CEO -

Contact us

 This email address is being protected from spambots. You need JavaScript enabled to view it.

Perth, Australia

Ph: +61 8 9212 2200

Cambridge, MA, USA

Ph: +1 617 945 8307