Please browse here to find research papers published by our clients utilising Ozgene mice.


1. Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action. (KI non-conditional)
Cooney, GJ.; James, DE; Langdon, WY; Molero, JC; Thien, CB; Turner, N
Diabetes, 2006 Dec;55(12):341
Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, NSW 2010, Australia.
2. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. (KO conditional)
Andersen, B.; Bhandari, A; Gill, GN; Lin, KK; Lu, Z; Roop, DR; Spencer, JA; Wang, N; Wertz, P; Xu, X; Yu, Z
Dev Biol, 2006 Nov 1;299(1):122-36. Epub 2006 Jul
Departments of Medicine and Biological Chemistry, University of California, Irvine, CA 92697-4030, USA.
3. A novel SV40 TAg transgenic model of asbestos-induced mesothelioma: malignant transformation is dose dependent. (Tg pronuclear injection)
Dunham, M; Koentgen, F; Lake, RA.; Robinson, BW; Robinson, C; Segal, A; Sherwood, A; van, Bruggen I
Cancer Res, 2006 Nov 15;66(22):10786
School of Medicine and Pharmacology and Western Australian Institute for Medical Research, University of Western Australia, Perth, Australia.
4. Renin enhancer is critical for control of renin gene expression and cardiovascular function. (KO non-conditional)
Adams, DJ; Arends, MJ; Head, GA; Kontgen, F; Lovicu, FJ; Markus, MA; Mayorov, DN; Morris, BJ.; Thiru, S; van, der Weyden L
J Biol Chem, 2006 Oct 20;281(42):31753-61. Epub 2006 Au
School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.
5. Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies (KI non-conditional)
Lee, H; Mackay, CR.; Mackay, F; Newton, R; Padkjaer, SB; Quan, A; So, T; Thatcher, J; Vogelzang, A; Whitfeld, PL; Zahra, D; Zwirner J,Koentgen F
Nature Biotechnology, 2006 Oct;24(10):1279-84. Epub 2006 Sep
Immunology and Inflammation Department, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.
6. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. (KO conditional)
Brehm, MA; Rock, KL.; Towne, CF; York, IA; Zendzian, S
Proc Natl Acad Sci U S A, 2006 Jun 13;103(24):9202-7. Epub 2006 Ju
Department of Pathology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
7. Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis. (Tg pronuclear injection)
Andrikopoulos, S.; Fam, BC; Favaloro, J; Kebede, M; Lamont, BJ; Massinet, H; Papapostolou, S; Proietto, J; Visinoni, S; Weinrich, B
Endocrinology, 2006 Jun;147(6):2764-72. Epub 2006 Feb
Department of Medicine (Austin Health and Northern Health), University of Melbourne, Heidelberg Repatriation Hospital, Heidelberg Heights, Victoria 3081, Australia.
8. Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination. (KO/KI)
Alexander, WS.; Binder, MD; Butzkueven, H; Cate, HS; Cooper, H; Croker, B; Emery, B; Kilpatrick, TJ.; Marriott, M; Merson, T; Murray, S; Snell, C; Soo, PY; Zhang, JG
Proc Natl Acad Sci U S A, 2006 May 16;103(20):7859-64. Epub 2006 Ma
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
9. Dph3, a small protein required for diphthamide biosynthesis, is essential in mouse development. (KO non-conditional)
Kulkarni, AB; Leppla, SH.; Liu, S; Sreenath, T; Ward, JM; Wiggins, JF
Mol Cell Biol, 2006 May;26(10):3835
Bacterial Toxins and Therapeutics Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
10. Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. (KO conditional)
Duester, G.; Molotkov, A; Molotkova, N
Development, 2006 May;133(10):1901-10. Epub 2006 Apr
Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
11. Gout-associated uric acid crystals activate the NALP3 inflammasome. (KO/KI)
Martinon, F; Mayor, A; Petrilli, V; Tardivel, A; Tschopp, J.
Nature, 2006 Mar 9;440(7081):237-41. Epub 2006 Jan
Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.

11 Publication(s)