Please browse here to find research papers published by our clients utilising Ozgene mice.


1. Testis Development, Fertility, and Survival in Ethanolamine Kinase 2-Deficient Mice. (KO conditional)
Gustin, SE; Harley, VR; Koopman, PA; McClive, PJ; Sinclair, AH.; Western, PS
Endocrinology, 2008 Dec;149(12):6176-86. Epub 2008 Aug
Murdoch Children's Research Institute, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.
2. Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens. (Bruce4 ES cells)
Basaraba, RJ; Bogdan, C; El, Kasmi KC; Fitzgerald, KA; Henao-Tamayo, M; Kanneganti, TD; Kaplan, G; K├Ânig, T; Koo, MS; Murray, PJ.; Orme, IM; Pesce, JT; Qualls, JE; Schleicher, U; Smith, AM; Thompson, RW; Tuomanen, EI; Wynn, TA
Nat Immunol, 2008 Dec;9(12):1399-406. Epub 2008 No
Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38015, USA.
3. Osteoclast inhibitory lectin (OCIL), an immune cell product that is required for normal bone physiology in vivo. (KO conditional)
Cipetic, M; Gillespie, MT.; Kartsogiannis, V; Ly, C; Martin, TJ; McGregor, NE; Ng, KW; Poulton, IJ; Quinn, JM; Saleh, H; Sims, NA; Smyth, MJ; Walker, EC; Wallace, ME; Zhou, H
J Biol Chem, 2008 Nov 7;283(45):30850-60. Epub 2008 Se
St. Vincent's Institute, 9 Princes Street, Fitzroy, Victoria 3065, Australia.
4. ZNF397, a new class of interphase to early prophase-specific, SCAN-zinc-finger, mammalian centromere protein. (KO conditional)
Bailey, SL; Chang, SC; Choo, KH; Earle, E; Graham, AN; Griffiths, B; Kalitsis, P.; Saffery, R
Chromosoma, 2008 Aug;117(4):367-80. Epub 2008 Mar
Chromosome and Chromatin Research, Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Victoria, Australia.
5. Rat aquaporin-5 4.3-Kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo. (Tg lentiviral)
Ann, D; Borok, Z.; Crandall, ED Ph D M D; Flodby, P; Liebler, JM; Minoo, P; Zhou, B
Am J Physiol Cell Physiol, 2008 Jul;295(1):C111-20. Epub 2008 Apr
Will Rogers Institute Pulmonary Research Center, Department of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
6. Conditional activation of a single-copy L1 transgene in mice by Cre. (KI conditional)
An, W; Boeke, JD.; Han, JS; Koentgen, F; Maitra, A; Schrum, CM
The High Throughput Biology Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
7. The extracellular matrix protein WARP is a novel component of a distinct subset of basement membranes. (KO/KI)
Allen, JM; Bateman, JF.; Brachvogel, B; Farlie, PG; Fitzgerald, J
Matrix Biol, 2008 May;27(4):295-305. Epub 2008 Jan
Murdoch Childrens Research Institute, University of Melbourne, Royal Children's Hospital, Parkville, Victoria, Australia.
8. The murine stanniocalcin 2 gene is a negative regulator of post-natal growth. (Not categorised)
Chang, AC; Gunning, PW; Hardeman, EC; Hook, J; Lemckert, FA; Little, DG; McDonald, MM; Nguyen, MA; Reddel, RR.
Endocrinology, 2008 May;149(5):2403-10. Epub 2008 Fe
Cancer Research Unit, The Children's Hospital, Westmead, New South Wales 2145, Australia.
9. Enamel Defects and Ameloblast-specific Expression in Enam Knock-out/lacZ Knock-in Mice. (KO/KI)
Feng, JQ; Hu, JC; Hu, Y; Hunter, GK; McKee, MD; Papagerakis, P; Simmer, JP.; Smith, CE; Wright, JT; Yamakoshi, F; Yamakoshi, Y
J Biol Chem, 2008 Apr 18;283(16):10858-71. Epub 2008 Fe
Department of Orthodontics and Pediatric Dentistry and Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan 48108, USA.
10. Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1. (Tg pronuclear injection)
Bonder, CS; Gamble, JR.; Hahn, CN; Li, X; Parsons, M; Pitson, SM; Proia, RL; Stankovic, M; Vadas, MA; Xia, P
Blood, 2008 Apr 1;111(7):3489-97. Epub 2008 Jan
Division of Human Immunology, Hanson Institute, Adelaide, Australia.
11. Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam). (KO/KI)
Feng, JQ; Hu, JC.; Hu, Y; Papagerakis, P; Simmer, JP; Ye, L
Eur J Oral Sci, 2008 Apr;116(2):113
Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor, MI 48108, USA.
12. Perturbed desmosomal cadherin expression in grainy head-like 1-null mice. (KO conditional)
Asquith, S; Auden, A; Caddy, J; Cerruti, L; Cunningham, JM; Ellis, S; Hislop, NR; Jane, SM.; Sinclair, R; Ting, SB; Wilanowski, T; Zhao, LL
EMBO J, 2008 Mar 19;27(6):886-97. Epub 2008 Feb
Rotary Bone Marrow Research Laboratories, Melbourne Health Research Directorate, Royal Melbourne Hospital, Parkville, Victoria, Australia.
13. The Ets transcription factor Elf5 specifies mammary alveolar cell fate. (Tg pronuclear injection)
and, Ormandy C.; Asselin-Labat, M; Blazek, K; Chodosh, L; Gardiner-Garden, M; Hilton, H; Kazlauskas, M; Lindeman, G; Naylor, M; Oakes, R; Pfeffer, P; Pritchard, M; Visvader, J
Genes & Development, 2008 Mar 1;22(5):58
Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
14. Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis. (KO conditional)
Bhandari, R; Juluri, KR; Resnick, AC; Snyder, SH.
Proc Natl Acad Sci U S A, 2008 Feb 19;105(7):2349-53. Epub 2008 Feb
Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
15. An important role for type III Interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity. (KO/KI)
Ank, N; Bartholdy, C; Chen, Z; Dagnaes-Hansen, F; Hartmann, R; Haugen, H; Iversen, MB; Jensen, UB; Klucher, K; Paludan, SR; Staeheli, P; Thomsen, AR
J Immunol, 2008 Feb 15;180(4):2474
Institute of Medical Microbiology and Immunology, University of Aarhus, Aarhus, Denmark.
16. Anoikis effector Bit1 negatively regulates Erk activity. (KO conditional)
Besch-Williford, C; Biliran, H; Kairouz-Wahbe, R; Khor, I; Luo, X; Oshima, R; Pascual, J; Ruoslahti, E.; Wankell, M
Proc Natl Acad Sci U S A, 2008 Feb 5;105(5):1528-32. Epub 2008 Jan
Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
17. Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice. (Tg pronuclear injection)
Jahroudi, N.; Kleinschmidt, AM; Nassiri, M; Pitt, BR; Stitt, MS; Wasserloos, K; Watkins, SC
J Biol Chem, 2008 Feb 1;283(5):2741-50. Epub 2007 Nov
Biology Department, Allegheny College, Meadville, PA 16335, USA.
18. The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells. (KI non-conditional)
Dagger, SA; Langdon, WY.; Oksvold, MP; Thien, CB
Mol Immunol, 2008 Feb;45(4):925-36. Epub 2007 Sep
School of Surgery and Pathology, University of Western Australia, Crawley, Western Australia 6009, Australia.

18 Publication(s)