Publications

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2020

Neuroscience. 2020 May 13;438:145-157. doi: 10.1016/j.neuroscience.2020.05.007.

Pro-BDNF Knockout Causes Abnormal Motor Behaviours and Early Death in Mice

H Li;LY L;Y Zhang;Y Lim;M Rahman;A Beck;M Al-Hawwas;S Feng;L Bobrovskaya;XF Zhou

Service type: Knockout mice

2016

PLoS Genet. 2016 Mar 15;12(3):e1005907. doi: 10.1371/journal.pgen.1005907. eCollection 2016.

A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis.

C Spilker;S Nullmeier;KM Grochowska;A Schumacher;I Butnaru;T Macharadze;GM Gomes;P Yuanxiang;G Bayraktar;C Rodenstein;C Geiseler;A Kolodziej;J Lopez-Rojas;D Montag;F Angenstein;J Bär;W D'Hanis;T Roskoden;M Mikhaylova;E Budinger;FW Ohl;O Stork;AC Zenclussen;A Karpova;H Schwegler;MR Kreutz

Service type: Knockout mice

2018

Sci Rep. 2018 Jan 23;8(1):1408. doi: 10.1038/s41598-018-19844-7.

Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice.

T Hisaoka;T Komori;T Kitamura;Y Morikawa

Service type: Knockout mice

2016

Metallomics. 2016 Jun 13.

Characterizing the molecular phenotype of an Atp7aT985I conditional knock-in mouse model for X-linked distal hereditary motor neuropathy (dHMNX).

G Perez-Siles;A Grant;M Ellis;C Ly;A Kidambi;M Khalil;RM Llanos;S Fontaine;AV Strickland;S Züchner;S Bermeo;E Neist;TC Brennan-Speranza;RI Takata;CE Speck-Martins;JF Mercer;GA Nicholson;ML Kennerson

Service type: Knock-in mice

2010

J Neuroscience 2010 Jan 6;30(1):9

Death-associated protein kinase-mediated cell death modulated by interaction with DANGER

Ahmad, AS;Doré, S;Hester, L;Kang, BN;Patterson, RL;Saleem, S;Snyder, SH.

Service type: Knockout mice

2012

Molecular neurodegeneration 2012 May 30;7(1):25. [Epub ahead of print]

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors.

KM Hinkle;M Yue;B Behrouz;JC Dachsel;SJ Lincoln;EE Bowles;JE Beevers;BN Dugger;CB Kent;B Winner;I Prots;K Nishioka;W Lin;DW Dickson;CG Janus;MJ Farrer;HL Melrose

Service type: Knockout mice

2021

FASEB J. 2021 Oct;35(10):e21940. doi: 10.1096/fj.202100944R.

BHLHE40 promotes macrophage pro-inflammatory gene expression and functions

Atif Zafar, Hang Pong Ng, Gun-Dong Kim, E Ricky Chan, Ganapati H Mahabeleshwar

Service type: Knockout mice

2019

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):193-205. doi: 10.1016/j.bbadis.2018.08.018. Epub 2018 Aug 16.

Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice.

E Jeanclos;M Albersen;RJJ Ramos;A Raab;C Wilhelm;L Hommers;KP Lesch;NM Verhoeven-Duif;A Gohla

Service type: Knockout mice

2017

PLoS One. 2017 Jan 12;12(1):e0168416. doi: 10.1371/journal.pone.0168416. eCollection 2017.

First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15.

JK Low;A Ambikairajah;K Shang;DA Brown;VW Tsai;SN Breit;T Karl

Service type: Knockout mice

2017

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1183-1188. doi: 10.1073/pnas.1618627114. Epub 2017 Jan 17.

α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.

SS Kang;Z Zhang;X Liu;FP Manfredsson;L He;PM Iuvone;X Cao;YE Sun;L Jin;K Ye

Service type: Knockout mice