Publications

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2008

EMBO J 2008 Mar 19;27(6):886-97. Epub 2008 Feb

Perturbed desmosomal cadherin expression in grainy head-like 1-null mice.

Asquith, S;Auden, A;Caddy, J;Cerruti, L;Cunningham, JM;Ellis, S;Hislop, NR;Jane, SM.;Sinclair, R;Ting, SB;Wilanowski, T;Zhao, LL

Service type: Knockout mice

2008

Proc Natl Acad Sci U S A 2008 Feb 19;105(7):2349-53. Epub 2008 Feb

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.

Bhandari, R;Juluri, KR;Resnick, AC;Snyder, SH.

Service type: Knockout mice

2008

J Immunol 2008 Feb 15;180(4):2474

An important role for type III Interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity.

Ank, N;Bartholdy, C;Chen, Z;Dagnaes-Hansen, F;Hartmann, R;Haugen, H;Iversen, MB;Jensen, UB;Klucher, K;Paludan, SR;Staeheli, P;Thomsen, AR

Service type: Knock-in mice

2008

Proc Natl Acad Sci U S A 2008 Feb 5;105(5):1528-32. Epub 2008 Jan

Anoikis effector Bit1 negatively regulates Erk activity.

Besch-Williford, C;Biliran, H;Kairouz-Wahbe, R;Khor, I;Luo, X;Oshima, R;Pascual, J;Ruoslahti, E.;Wankell, M

Service type: Knockout mice

2008

Mol Immunol 2008 Feb;45(4):925-36. Epub 2007 Sep

The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells.

Dagger, SA;Langdon, WY.;Oksvold, MP;Thien, CB

Service type: Knock-in mice

2008

J Biol Chem 2008 Feb 1;283(5):2741-50. Epub 2007 Nov

Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice.

Jahroudi, N.;Kleinschmidt, AM;Nassiri, M;Pitt, BR;Stitt, MS;Wasserloos, K;Watkins, SC

Service type: Transgenic mice

2007

Cell 2007 Nov 16;131(4):682

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

Ahmed, AU;Benetatos, CA;Brink, R;Callus, BA;Chau, D;Chunduru, SK;Condon, SM;Feltham, R;Khan, N;Koentgen, F;Leverkus, M;McKinlay, M;Schneider, P;Silke, J.;Tergaonkar, V;Vaux, DL;Vince, JE;Wong, WW

Service type: Not applicable

2007

Blood 2007 Nov 15;110(10):3753-62. Epub 2007 Aug

NOTCH1 pathway activation is an early hallmark of SCL T-leukemogenesis.

Begley, CG.;Brake, RL;Duhrsen, U;Gothert, JR;Izon, DJ.;Smeets, M

Service type: Transgenic mice

2007

Proc Natl Acad Sci U S A 2007 Sep 11;104(37):14759-64. Epub 2007 Se

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.

Batten, M;Biben, C;Groom, J;Harvey, RP;Leung, H;Li, M;Mackay, CR;Mackay, F.;Martínez-A, C;Martínez-Muñoz, L;Mellado, M;Ransohoff, RM;Sierro, F;Woehl, B

Service type: Knockout mice

2007

J Clin Invest 2007 Jun;117(6):1627-36. Epub 2007 May

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair.

Farmer, PJ;Fosang, AJ.;Golub, SB;Lawlor, KE;Little, CB;Meeker, CT;Smith, SM

Service type: Knock-in mice