Publications

  • Reset

2024

Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1.

Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions

Adam R Wolfe, Tiantian Cui, Sooin Baie, Sergio Corrales-Guerrero, Amy Webb, Veronica Castro-Aceituno, Duan-Liang Shyu, Joanna M Karasinska, James T Topham, Daniel J Renouf, David F Schaeffer, Megan Halloran, Rebecca Packard, Ryan Robb, Wei Chen, Nicholas Denko, Michael Lisanti, Timothy C Thompson, Philippe Frank, Terence M Williams

Service type: Knockout mice

2024

Development. 2024 Mar 1;151(5):dev202617. doi: 10.1242/dev.202617. Epub 2024 Mar 6.

ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development

Sophia Y Y Mah, Hannah K Vanyai, Connie S N Li-Wai-Suen, Alexandra L Garnham, Jessica Wynn, Maria I Bergamasco, Shezlie Malelang, Stephen Wilcox, Christine Biben, Gordon K Smyth, Tim Thomas, Anne K Voss

Service type: Knockout mice

2024

Hepatology. 2024 Feb 16. doi: 10.1097/HEP.0000000000000782. Online ahead of print.

Stellate cell-specific adhesion molecule protocadherin 7 regulates sinusoidal contraction

James K Carter, Ming-Chao Tsai , Nicholas Venturini, Jiangting Hu, John J Lemasters, Miguel Torres Martin, Daniela Sia, Shuang Wang, Youngmin A Lee, Scott L Friedman

Service type: Knockout mice

2024

Am J Physiol Lung Cell Mol Physiol. 2024 Feb 13. doi: 10.1152/ajplung.00383.2023.

Disruption of the SP-A/SP-R210L (Myo18Aα) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation

Zhiwei Guan, Brandon Worth, Todd M Umstead, Shaili Amatya, Jennifer Booth, Zissis C Chroneos

Service type: Knockout mice

2024

Mucosal Immunol. 2024 Feb 7:S1933-0219(24)00007-2. doi: 10.1016/j.mucimm.2024.02.003.

A Trefoil factor 3-Lingo2 axis restrains proliferative expansion of type-1 T helper cells during GI nematode infection

Lucas M Ethgen, Christopher Pastore, Cailu Lin, Danielle R Reed, Li-Yin Hung, Bonnie Douglas, Dominic Sinker, De'Broski R Herbert, Nicole M Belle

Service type: Knock-in mice

2023

NPJ Parkinsons Dis. 2023 Dec 18;9(1):167. doi: 10.1038/s41531-023-00609-7.

Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice

Mengfei Bu, Jordan Follett, Isaac Deng, Igor Tatarnikov, Shannon Wall, Dylan Guenther, Melissa Maczis, Genevieve Wimsatt, Austen Milnerwood, Mark S Moehle, Habibeh Khoshbouei, Matthew J Farrer

Service type: Knock-in mice

2023

EMBO Rep. 2023 Nov 14:e57972. doi: 10.15252/embr.202357972. Online ahead of print.

MAPL loss dysregulates bile and liver metabolism in mice

Vanessa Goyon, Aurèle Besse-Patin, Rodolfo Zunino, Olesia Ignatenko, Mai Nguyen, Étienne Coyaud, Jonathan M Lee, Bich N Nguyen, Brian Raught, Heidi M McBride

Service type: Knock-in mice

2023

Am J Physiol Gastrointest Liver Physiol. 2023 Nov 14. doi: 10.1152/ajpgi.00140.2023. Online ahead of print.

Defining a timeline of colon pathologies after keratin 8 loss: Rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation

Maria A. Ilomäki, Lauri Polari, Carl-Gustaf A. Stenvall, Mina Tayyab, Kirah Kähärä, Karen M. Ridge, Diana M. Toivola

Service type: Knockout mice

2023

Am J Hum Genet. 2023 Nov 3:S0002-9297(23)00358-0. doi: 10.1016/j.ajhg.2023.10.005. Online ahead of print.

Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need

Dominique L Brooks, Madelynn N Whittaker, Ping Qu, Kiran Musunuru, Rebecca C Ahrens-Nicklas, Xiao Wang

Service type: Knock-in mice

2023

Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2306761120. doi: 10.1073/pnas.2306761120. Epub 2023 Sep 27.

Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation

Gianluca Scarno, Julija Mazej, Mattia Laffranchi, Chiara Di Censo, Irene Mattiola, Arianna M Candelotti, Giuseppe Pietropaolo, Helena Stabile, Cinzia Fionda, Giovanna Peruzzi, Stephen R Brooks, Wanxia Li Tsai, Yohei Mikami, Giovanni Bernardini, Angela Gismondi, Silvano Sozzani, James P Di Santo, Christian A J Vosshenrich, Andreas Diefenbach, Massimo Gadina, Angela Santoni, Giuseppe Sciumè

Service type: Knockout mice