|Strain||Outbred, Swiss mouse heritage.|
- MHC haplotype: Outbred
- Complement factor: some mice are C5 deficient (See: ARC(S)-5 strain info)
- The strain is known for its large litters, with an average of 11-12 young per litter, making them ideal for studies involving breeding or reproductive research.
- Female mice of the ARC(S) strain are often used as foster mothers due to their good maternal behaviour.
- They can display aggressive behaviour when handled after 7 weeks of age.
- In terms of physical traits, ARC(S) mice are robust, healthy, and generally hardy, which makes them suitable for various experimental purposes.
- The ARC(S) strain traces its origin to the Hauschka Ha/ICR stock initiated in1948 at the Institute for Cancer Research (ICR) in Philadelphia from “Swiss” mice of Rockefeller.
- The stock was transferred to Charles River Breeding Laboratories in 1959 and described as an outbred CD-1(ICR) stock.
- Mice from the colony were transferred to the Animal Resources Centre (ARC) in Canning Vale, Western Australia in 1981.
- In 2023, stock was transferred to Ozgene ARC.
- This strain is often used as sentinels.
- Females may be used as recipients for non-albino embryo transfers.
- These mice may be useful for toxicology and pharmacology screens.
- Mouse images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.