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2021

Sci Rep. 2021 Apr 29;11(1):9319. doi: 10.1038/s41598-021-88895-0.

Inducible knockout of Clec16a in mice results in sensory neurodegeneration

Heather S Hain, Rahul Pandey, Marina Bakay, Bryan P Strenkowski, Danielle Harrington, Micah Romer, William W Motley, Jian Li, Eunjoo Lancaster, Lindsay Roth, Judith B Grinspan, Steven S Scherer, Hakon Hakonarson

Service type: Knockout mice

2021

Int J Mol Sci. 2021 Mar 26;22(7):3409. doi: 10.3390/ijms22073409.

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

Christian Griñán-Ferré, Júlia Companys-Alemany, Júlia Jarné-Ferrer, Sandra Codony, Celia González-Castillo, Daniel Ortuño-Sahagún, Lluïsa Vilageliu, Daniel Grinberg, Santiago Vázquez, Mercè Pallàs

Service type: Humanized mice

2021

Cancers (Basel). 2021 Mar 14;13(6):1288. doi: 10.3390/cancers13061288.

p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair

Keane K Y Lai, Xiaohui Hu, Keisuke Chosa, Cu Nguyen, David P Lin, Keith K Lai, Nobuo Kato, Yusuke Higuchi, Sarah K Highlander, Elizabeth Melendez, Yoshihiro Eriguchi, Patrick T Fueger, Andre J Ouellette, Nyam-Osor Chimge, Masaya Ono, Michael Kahn

Service type: Knock-in mice

2021

bioRxiv. 2021 Mar 02. doi: https://doi.org/10.1101/2021.03.01.433470

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

Camilla M. Reehorst, Rebecca Nightingale, Ian Y. Luk, Laura Jenkins, Frank Koentgen, David S. Williams, Charbel Darido, Fiona Tan, Holly Anderton, Michael Chopin, Kael Schoffer, Moritz F. Eissmann, Michael Buchert, Dmitri Mouradov, Oliver M Sieber, Matthias Ernst, Amardeep S. Dhillon, John M. Mariadason

Service type: Knockout mice

2021

Immunohorizons. 2021 Jan 18;5(1):25-32. doi: 10.4049/immunohorizons.2000107.

Generation of an HLA-DQ2.5 Knock-In Mouse

Alisa E Dewan, Frank Koentgen, Marie K Johannesen, M Fleur du Pre, Ludvig M Sollid

Service type: Humanized mice

2021

Nat Commun. 2021 Jan 15;12(1):383. doi: 10.1038/s41467-020-20669-0.

The p63 C-terminus is essential for murine oocyte integrity

Anna Maria Lena, Valerio Rossi, Susanne Osterburg, Artem Smirnov, Christian Osterburg, Marcel Tuppi, Angela Cappello, Ivano Amelio, Volker Dötsch, Massimo De Felici, Francesca Gioia Klinger, Margherita Annicchiarico-Petruzzelli, Herbert Valensise, Gerry Melino, Eleonora Candi

Service type: Knockout mice

2021

EMBO J. 2021 Jan 7;e105784. doi: 10.15252/embj.2020105784. Online ahead of print.

ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation

Marcus Borenäs, Ganesh Umapathy, Wei-Yun Lai, Dan E Lind, Barbara Witek, Jikui Guan, Patricia Mendoza-Garcia, Tafheem Masudi, Arne Claeys, Tzu-Po Chuang, Abeer El Wakil, Badrul Arefin, Susanne Fransson, Jan Koster, Mathias Johansson, Jennie Gaarder, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer

Service type: Knock-in mice

2021

J Clin Invest. 2021 Jan 4;131(1):e135124. doi: 10.1172/JCI135124.

Defective lysosome reformation during autophagy causes skeletal muscle disease

Meagan J McGrath, Matthew J Eramo, Rajendra Gurung, Absorn Sriratana, Stefan M Gehrig, Gordon S Lynch, Sonia Raveena Lourdes, Frank Koentgen, Sandra J Feeney, Michael Lazarou, Catriona A McLean, Christina A Mitchell

Service type: Knockout mice

2020

PLoS One. 2020 Dec 31;15(12):e0244792. doi: 10.1371/journal.pone.0244792. eCollection 2020.

Intense light as anticoagulant therapy in humans

Y Oyama;S Shuff;P Davizon-Castillo;N Clendenen;T Eckle

Service type: Knockout mice

2020

Endocrinology. 2020 Dec 29;bqaa246. doi: 10.1210/endocr/bqaa246. Online ahead of print.

Using a reporter mouse to map known and novel sites of GLP-1 receptor expression in peripheral tissues of male mice

DB Andersen;KV Grunddal;J Pedersen;RE Kuhre;ML Lund;JJ Holst;C Ørskov

Service type: Knock-in mice

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