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2021

Endocrinology. 2021 Aug 26;bqab179. doi: 10.1210/endocr/bqab179. Online ahead of print.

Cochlear fibrocyte and osteoblast lineages expressing type 2 deiodinase identified with a Dio2 CreERt2 allele

Lily Ng, Ye Liu, Hong Liu, Douglas Forrest

Service type: Knock-in mice

2021

J Neurosci. 2021 Aug 11;41(32):6850-6863. doi: 10.1523/JNEUROSCI.3005-20.2021. Epub 2021 Jul 1.

Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation

C H H Hor, J C W Lo, A L S Cham, W Y Leong, E L K Goh

Service type: Knockout mice

2021

J Immunol. 2021 Aug 1;207(3):902-912. doi: 10.4049/jimmunol.2001251. Epub 2021 Jul 23.

Macrophage-Derived MicroRNA-21 Drives Overwhelming Glycolytic and Inflammatory Response during Sepsis via Repression of the PGE 2/IL-10 Axis

Paulo De Melo, Annie Rocio Pineros Alvarez, Xiang Ye, Amondrea Blackman, Jose Carlos Alves-Filho, Alexandra I Medeiros, Jeffrey Rathmell, Heather Pua, C Henrique Serezani

Service type: Knockout mice

2021

Endocrinol Diabetes Metab. 2021 Jun 22;4(3):e00278. doi: 10.1002/edm2.278. eCollection 2021 Jul.

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Aowen Zhuang , Felicia Y T Yap, Danielle J Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A Penfold, Karly C Sourris, Melinda T Coughlan, Benjamin L Schulz, Josephine M Forbes

Service type: Transgenic mice

2021

Cell Death Dis. 2021 Jun 21;12(7):637. doi: 10.1038/s41419-021-03906-2.

Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels

Agnes Fütterer, Amaia Talavera-Gutiérrez, Tirso Pons, Jesús de Celis, Julio Gutiérrez, Verónica Domínguez Plaza, Carlos Martínez-A

Service type: Knockout mice

2021

Nat Commun. 2021 Jun 18;12(1):3754. doi: 10.1038/s41467-021-23909-z.

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

Michael Lacy, Christina Bürger, Annelie Shami, Maiwand Ahmadsei, Holger Winkel, Katrin Nitz, Claudia M van Tiel, Tom T P Seijkens, Pascal J H Kusters, Ela Karshovka, Koen H M Prange, Yuting Wu, Sanne L N Brouns, Sigrid Unterlugauer, Marijke J E Kuijpers, Myrthe E Reiche, Sabine Steffens, Andreas Edsfeldt, Remco T A Megens, Johan W M Heemskerk, Isabel Goncalves, Christian Weber, Norbert Gerdes, Dorothee Atzler, Esther Lutgens

Service type: Knockout mice

2021

Biol Psychiatry. 2021 Jun 7;S0006-3223(21)01363-9. doi: 10.1016/j.biopsych.2021.05.027.

Developmental and Behavioral Phenotypes in a Mouse Model of DDX3X Syndrome

Andrea Boitnott, Marta Garcia-Forn, Dévina C Ung, Kristi Niblo, Danielle Mendonca, Yeaji Park, Michael Flores, Sylvia Maxwell, Jacob Ellegood, Lily R Qiu, Dorothy E Grice, Jason P Lerch, Mladen-Roko Rasin, Joseph D Buxbaum, Elodie Drapeau, Silvia De Rubeis

Service type: Knockout mice

2021

J Exp Med. 2021 Jun 7;218(6):e20210008. doi: 10.1084/jem.20210008.

PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling

Jiwen Li, Catharina Conrad, Tingting W Mills, Nathaniel K Berg, Boyun Kim, Wei Ruan, Jae W Lee, Xu Zhang, Xiaoyi Yuan, Holger K Eltzschig.

Service type: Knockout mice

2021

Biomedicines. 2021 Jun 1;9(6):630. doi: 10.3390/biomedicines9060630.

MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva

Huili Lyu, Cody M Elkins, Jessica L Pierce, C Henrique Serezani, Daniel S Perrien

Service type: Knock-in mice

2021

Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):28. doi: 10.1167/iovs.62.7.28.

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump

Diego G Ogando, Rajalekshmy Shyam, Edward T Kim, Yen-Chiao Wang, Chia-Yang Liu, Joseph A Bonanno

Service type: Knockout mice

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