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Publications

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2022

Dev Cell. 2022 Aug 22;57(16):1957-1975.e9. doi: 10.1016/j.devcel.2022.07.012.

DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

Bruno Frederico, Isaura Martins, Diana Chapela, Francesca Gasparrini, Probir Chakravarty, Tobias Ackels, Cécile Piot, Bruna Almeida, Joana Carvalho, Alessandro Ciccarelli, Christopher J Peddie, Neil Rogers, James Briscoe, François Guillemot, Andreas T Schaefer, Leonor Saúde, Caetano Reis E Sousa

Service type: Knock-in mice

2022

Immunity. 2022 Aug 17;S1074-7613(22)00354-5. doi: 10.1016/j.immuni.2022.07.019. Online ahead of print.

Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

Marco A Ataide, Konrad Knöpper, Paulina Cruz de Casas, Milas Ugur, Sarah Eickhoff, Mangge Zou, Haroon Shaikh, Apurwa Trivedi, Anika Grafen, Tao Yang, Immo Prinz, Knut Ohlsen, Mercedes Gomez de Agüero, Andreas Beilhack, Jochen Huehn, Mauro Gaya, Antoine-Emmanuel Saliba, Georg Gasteiger, Wolfgang Kastenmüller

Service type: Knock-in mice

2022

Stem Cell Reports. 2022 Aug 1;S2213-6711(22)00364-2. doi: 10.1016/j.stemcr.2022.07.005. Online ahead of print.

Exclusive generation of rat spermatozoa in sterile mice utilizing blastocyst complementation with pluripotent stem cells

Joel Zvick, Monika Tarnowska-Sengül, Adhideb Ghosh, Nicola Bundschuh, Pjeter Gjonlleshaj, Laura C Hinte, Christine L Trautmann, Falko Noé, Xhem Qabrati, Seraina A Domenig, Inseon Kim, Thomas Hennek, Ferdinand von Meyenn, Ori Bar-Nur

Service type: goGermline™ embryos

2022

Mol Cell. 2022 Jun 16;S1097-2765(22)00540-8. doi: 10.1016/j.molcel.2022.06.004. Online ahead of print.

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1

Samuel A Killackey, Yuntian Bi, Fraser Soares, Ikram Hammi, Nathaniel J Winsor, Ali A Abdul-Sater, Dana J Philpott, Damien Arnoult, Stephen E Girardin

Service type: Knockout mice

2022

Oncoimmunology. 2022 Jun 13;11(1):2081009. doi: 10.1080/2162402X.2022.2081009. eCollection 2022.

Intratumoural administration of an NKT cell agonist with CpG promotes NKT cell infiltration associated with an enhanced antitumour response and abscopal effect

Kef K Prasit, Laura Ferrer-Font, Olivia K Burn, Regan J Anderson, Benjamin J Compton, Alfonso J Schmidt, Johannes U Mayer, Chun-Jen J Chen, Nathaniel Dasyam, David S Ritchie, Dale I Godfrey, Stephen R Mattarollo, P Rod Dundar, Gavin F Painter, Ian F Hermans

Service type: Transgenic mice

2022

Cell Biosci. 2022 Jun 7;12(1):84. doi: 10.1186/s13578-022-00804-8.

Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing

Julio Gutiérrez, Karel H M van Wely, Carlos Martínez-A

Service type: Knockout mice

2022

Mol Neurodegener. 2022 Jun 11;17(1):41. doi: 10.1186/s13024-022-00547-7.

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H Suh, Elliot Thomsen, Jason Dugas, Michelle E Pizzo, Sarah L DeVos, Timothy K Earr, Chia-Ching Lin, Sonnet Davis, Connie Ha, Amy Wing-Sze Leung, Hoang Nguyen, Roni Chau, Ernie Yulyaningsih, Isabel Lopez, Hilda Solanoy, Shababa T Masoud, Chun-Chi Liang, Karin Lin, Giuseppe Astarita, Nathalie Khoury, Joy Yu Zuchero, Robert G Thorne, Kevin Shen, Stephanie Miller, Jorge J Palop, Dylan Garceau, Michael Sasner, Jennifer D Whitesell, Julie A Harris, Selina Hummel, Johannes Gnörich, Karin Wind, Lea Kunze, Artem Zatcepin, Matthias Brendel, Michael Willem, Christian Haass, Daniel Barnett, Till S Zimmer, Anna G Orr, Kimberly Scearce-Levie, Joseph W Lewcock, Gilbert Di Paolo, Pascal E Sanchez

Service type: Knock-in mice

2022

Mucosal Immunol. 2022 May;15(5):964-976. doi: 10.1038/s41385-022-00550-7. Epub 2022 Jul 22.

Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis

Vladimir Grubišić, Vedrana Bali, David E Fried, Holger K Eltzschig, Simon C Robson, Michelle S Mazei-Robison, Brian D Gulbransen

Service type: Knockout mice

2022

Eur J Immunol. 2022 Apr 7. doi: 10.1002/eji.202149665. Online ahead of print.

Hobit and Blimp-1 regulate T RM abundance after LCMV infection by suppressing tissue exit pathways of T RM precursors

Loreto Parga-Vidal, Renske L R E Taggenbrock, Ammarina Beumer-Chuwonpad, Hajar Aglmous, Natasja A M Kragten, Felix M Behr, Astrid A Bovens, Rene A W van Lier, Regina Stark, Klaas P J M van Gisbergen

Service type: Knock-in mice

2022

Sex Dev. 2022 Mar 18;1-13. doi: 10.1159/000522668. Online ahead of print.

Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice

Liang Zhao, Ella Thomson, Ee T Ng, Enya Longmuss, Terje Svingen, Stefan Bagheri-Fam, Alexander Quinn, Vincent R Harley, Leonard C Harrison, Emanuele Pelosi, Peter Koopman

Service type: Knockout mice