2023
Nat Metab. 2023 Feb 16. doi: 10.1038/s42255-023-00736-8. Online ahead of print.
PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages
Service type: Knock-in mice
2023
EMBO J. 2023 Feb 15;42(4):e112118. doi: 10.15252/embj.2022112118. Epub 2023 Jan 3.
A critical period of prehearing spontaneous Ca2+ spiking is required for hair-bundle maintenance in inner hair cells
Service type: Knock-in mice
2023
PLoS One. 2023 Feb 9;18(2):e0280792. doi: 10.1371/journal.pone.0280792. eCollection 2023.
Mutation of regulatory phosphorylation sites in PFKFB2 does not affect the anti-fibrotic effect of metformin in the kidney
Service type: Knock-in mice
2023
Bone. 2023 Feb;167:116636. doi: 10.1016/j.bone.2022.116636. Epub 2022 Nov 30.
Targeted postnatal knockout of Sclerostin using a bone-targeted adeno-associated viral vector increases bone anabolism and decreases canalicular density
Service type: Knockout mice
2023
mBio 2023 Jan 24;e0354222. doi: 10.1128/mbio.03542-22. Online ahead of print.
Deletion of the Transcriptional Coactivator HCF-1 In Vivo Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation
Service type: Knock-in mice
2023
Sci Rep. 2023 Jan 21;13(1):1215. doi: 10.1038/s41598-023-27782-2.
Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice
Service type: Knock-in mice
2022
Am J Physiol Endocrinol Metab 2022 Dec 1;323(6):E467-E479. doi: 10.1152/ajpendo.00401.2021. Epub 2022 Sep 21.
Genetic ablation of the preptin-coding portion of Igf2 impairs pancreatic function in female mice
Service type: Knock-in mice
2022
Curr Biol. 2022 Nov 21;32(22):4832-4841.e5. doi: 10.1016/j.cub.2022.09.037. Epub 2022 Oct 10.
Secretin receptor deletion in the subfornical organ attenuates the activation of excitatory neurons under dehydration
Service type: Knockout mice
2022
J Physiol. 2022 Nov;600(22):4827-4848. doi: 10.1113/JP283811. Epub 2022 Oct 19.
Chronic reduction of store operated Ca2+ entry is viable therapeutically but is associated with cardiovascular complications
Service type: Knock-in mice
2022
Sci Immunol. 2022 Oct 28;7(76):eabm8389. doi: 10.1126/sciimmunol.abm8389. Epub 2022 Oct 28.
Long-lived plasma cells accumulate in the bone marrow at a constant rate from early in an immune response
Service type: Knock-in mice