The C57BL/10ScSn strain traces its origins back to the original work of C.C. Little in 1921, who created this strain through a mating of Miss Abbie Lathrop’s stock. The strain was then passed on to W.L. Russell, and subsequently to J.P. Scott (Sc) at F26 as a separate subline, and later to George Snell (Sn) at F35-36.
The C57BL/10ScSn strain has been widely used in various research fields and has numerous applications due to its unique genetic characteristics, making it a valuable tool in advancing scientific knowledge and understanding various biological processes, diseases, and therapies.