BALB/c

BALB/c

BALB/c

Strain details
NomenclatureBALB/cOzarc
Common nameBALBc
SynonymsC, BALB, BALB/c
StrainInbred
Coat ColourAlbino (A/A Tyrp1b/ Tyrp1b Tyrc/Tyrc)
SpeciesMouse
Genetic background-
LocationArea Oz5

Strain descriptions

  • MHC haplotype: H2Kd
  • Complement factor: C5 normal
  • Low incident of mammary tumours.
  • Amyloidosis in older males (40%)
  • Aggressiveness observed in male stock from 6 weeks of age and female breeders.
  • Fighting amongst males increases when cohorts are divided into smaller groups.
  • High social dominance exhibited by males in presence of females resulting in high aggression.
  • Low mortality after neonatal thymectomy.
  • Cystitis.
  • Barbering after 7 weeks.
  • Originally: developed by MacDowell (1923) who inbred from Bagg albino. To Snell (1932) at F26
  • ARC received from University of Western Australia at F45 (1981).
  • ARC transferred strain to Ozgene ARC in 2023.
  • The BALB/c mouse is among the most widely used inbred models used in biomedical research, and is particularly utilized in immunology and infectious disease research. Their ability to produce plasma cell tumours within soft tissue is important in the production of monoclonal antibodies (mAbs).

Past ARC and transfer reports:

Current Ozgene ARC reports (from 01-Jun-2024)

  • Mouse images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.