C57BL/6JOzarc

Strain descriptions

MHC haplotype: H2K^b
Complement factor: C5 normal
Susceptible to the development of atheromatous lesion after 20 weeks on high fat diets.
Develops non-insulin dependent diabetes mellitus and hypertension when fed a high fat, high simple carbohydrate diet.
Glucose intolerance is due to spontaneous mutation in Nicotinamide Nucleotide Transhydrogenase (Nnt).
Generally refectory to many tumours and to many infectious agents.
Congenital abnormalities include microphthalmia, corneal opacities, anophthalmia and hydrocephalus.
Susceptible to imperforate vaginas and mucometra.
White spotting commonly observed in pigmentation.
Aggressiveness observed in male from 6 weeks of age and female breeders.
Fighting amongst males increases when cohorts are divided into smaller groups.
Barbering and ulcerative dermatitis observed.

The C57BL/6J inbred strain was created by Dr. CC Little from the mating of female 57 with male 52 from Miss Abbie Lathrop’s stock.
Ozgene ARC received the stock strain from ARC in 2023.

B6 mice is the most widely used inbred strain and the first to have its genome sequenced.

These mice are sold subject to The Jackson Laboratory’s Conditions of Use and also the Australian Patent Number (2004268530). Information regarding conditions of use is available at: JAX General Terms and Conditions
JAX mice are the gold standard for animal model research.
Ozgene ARC terms and Conditions

Mouse images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.