F344
F344
| Strain details | |
|---|---|
| Nomenclature | F344/Ozarc |
| Common name | F344 |
| Synonyms | Fischer 344 Rat |
| Strain | Inbred |
| Coat colour | Albino (a, B, c, h) |
| Species | Rat |
| Genetic background | - |
| Location | Area Oz4 |
| Weekly wean target | <10 males, <10 females |
Strain descriptions
- MHC Haplotype RT1lv1
- The most popular strain of rat for use in carcinogen evaluation
- Relatively low incidence of naturally occurring neoplasms.
- High responder to induced neoplasms via chemicals and/or irradiation.
- Glandular changes associated with the spontaneous interstitial cell tumours of the testis.
- Resistant to spontaneous autoimmune thyroiditis.
- Low incidence of nephritis.
- Good breeding performance.
- Young females are jumpy and don’t like being handled.
- Received as Germ Free animals from Charles River Breeding Laboratories, USA (1983).
- Charles River rederived F68 from NIH in 1960 to SPF status, NIH received as F51 (1950) from Heston. Heston from Columbia University, USA (1949). Originally developed as an inbred by Curtis (1920) at Columbia University Institute for Cancer Research, USA.
- Received from Animal Resource Centre (ARC), Western Australia in 2023.
- General multipurpose model, aging, safety and efficacy testing, surgical model, oncology, nutrition.
| F344 | F344/Ozarc | |
|---|---|---|
| WKS | MALE | FEMALE |
| 3 | 27 - 50 | 28 - 52 |
| 4 | 45 - 68 | 46 - 70 |
| 5 | 73 - 122 | 68 - 105 |
| 6 | 107 - 147 | 98 - 125 |
| 7 | 135 - 188 | 114 - 143 |
| 8 | 156 - 238 | 126 - 153 |
| 9 | 195 - 261 | 135 - 164 |
| 10 | 212 - 283 | 140 - 171 |
| 11 | 225 - 294 | 145 - 184 |
| 12 | 234 - 305 | 149 - 184 |
| 13 | 199 - 297 | 158 - 183 |
| 14 | 209 - 309 | 160 - 187 |
Past ARC reports:
Current Ozgene ARC reports (from 01-Jun-2023)
- This strain is housed in Area Oz4
- Please see Oz4 health reports on our Biosecurity page
- Animals are not allowed to be used for propagation.
- Ozgene ARC terms and Conditions
- Mouse images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.
- J Kanno , C Matsuoka, K Furuta, H Onodera, A Maekawa, Y Hayashi (1987) Glandular changes associated with the spontaneous interstitial cell tumor of the rat testes. 15(4):439-43.
