goGermline knockout & knock-in mice
d03; 100% ES cell derived mice
d03; Published in Genesis
d03; Awarded ISTT 3Rs prize
"The potentially significant impact that the widespread application and use of this transgenic technology provides, makes it a worthy inaugural winner of the ISTT 3Rs prize, the aim of which is to raise awareness of the beneficial 3Rs impact that transgenic technologies can have in relation to the use of animals for scientific research."
- ISTT 3Rs Committee
What is goGermline?
goGermline is a fast and efficient way to generate knockout and knock-in mice. It is a revolutionary technology that incorporates the use of goGermline embryos for injecting embryonic stem (ES) cells. goGermline eliminates competition with “host” embryos, resulting in 100% ES cell derived offspring.
Ozgene is the only company that can guarantee that only ES cell derived animals are produced at chimera breeding. All of our knockout and knock-in projects use goGermline, with significant benefits to germline efficiency, project timelines and animal welfare. To experience the goGermline benefits firsthand, enquire about a mouse project with us or order goGermline embryos to trial them in your facility.
Watch the video to learn more about goGermline and its benefits to investigators and animal welfare.
Contact us to discuss your goGermline project or to order goGermline embryos.