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2021

Biol Psychiatry. 2021 Jun 7;S0006-3223(21)01363-9. doi: 10.1016/j.biopsych.2021.05.027.

Developmental and Behavioral Phenotypes in a Mouse Model of DDX3X Syndrome

Andrea Boitnott, Marta Garcia-Forn, Dévina C Ung, Kristi Niblo, Danielle Mendonca, Yeaji Park, Michael Flores, Sylvia Maxwell, Jacob Ellegood, Lily R Qiu, Dorothy E Grice, Jason P Lerch, Mladen-Roko Rasin, Joseph D Buxbaum, Elodie Drapeau, Silvia De Rubeis

Service type: Knockout mice

2013

PloS one 2013 Nov 6;8(11):e78378. doi: 10.1371/journal.pone.0078378.

Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality.

MG Gall;Y Chen;AJ Vieira de Ribeiro;H Zhang;CG Bailey;DS Spielman;DM Yu;MD Gorrell

Service type: Knock-in mice

2023

Sci Rep. 2023 Jan 21;13(1):1215. doi: 10.1038/s41598-023-27782-2.

Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice

Ines Leca, Alexander William Phillips, Lyubov Ushakova, Thomas David Cushion, David Anthony Keays

Service type: Knock-in mice

2020

Pflugers Arch. 2020 Nov 16. doi: 10.1007/s00424-020-02491-1. Online ahead of print.

Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC

C Schnoz;S Moser;DV Kratschmar;A Odermatt;D Loffing-Cueni;J Loffing

Service type: Knock-in mice

2011

J Biol Chem 2011 Apr 15;286(15):13404-13. Epub 2011 Feb

The phosphoinositide kinase PIKfyve is vital in early embryonic development: Preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice

Delvecchio, K;Ikonomov, OC;Jin, JP;Rappolee, D;Sbrissa, D;Shisheva, A.;Xie, Y

Service type: Knockout mice

2016

Cell Rep. 2016 Aug 9;16(6):1664-76. doi: 10.1016/j.celrep.2016.07.005. Epub 2016 Jul 28.

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size.

RB Perry;I Rishal;E Doron-Mandel;AL Kalinski;KF Medzihradszky;M Terenzio;S Alber;S Koley;A Lin;M Rozenbaum;D Yudin;PK Sahoo;C Gomes;V Shinder;W Geraisy;EA Huebner;CJ Woolf;A Yaron;AL Burlingame;JL Twiss;M Fainzilber

Service type: Knockout mice

2013

Proceedings of the National Academy of Sciences of the United States of America 2013 Oct 1;110(40):16181-16186. Epub 2013 Sep 16.

Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction.

R Xu;BD Paul;DR Smith;R Tyagi;F Rao;AB Khan;DJ Blech;MS Vandiver;MM Harraz;P Guha;I Ahmed;N Sen;M Gallagher;SH Snyder

Service type: Knockout mice

2021

bioRxiv. 2021 Jan 19. doi: https://doi.org/10.1101/2021.01.19.426731

Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model

Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H. Suh, Elliot Thomsen, Jason Dugas, Michelle E. Pizzo, Sarah L. DeVos, Timothy K. Earr, Chia-Ching Lin, Sonnet Davis, Connie Ha, Hoang Nguyen, Roni Chau, Ernie Yulyaningsih, Hilda Solanoy, Shababa T. Masoud, Richard Liang, Karin Lin, Robert G. Thorne, Dylan Garceau, Jennifer D. Whitesell, Michael Sasner, Julie A. Harris, Kimberly Scearce-Levie, Joseph W. Lewcock, Gilbert Di Paolo, Pascal E. Sanchez.

Service type: Knock-in mice

2010

Am J Physiol Heart Circ Physiol 2010 Jan;298(1):H24-32. Epub 2009 Oct

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice

Broughton, BR;Diep, H;Drummond, GR.;Dusting, GJ;Hooker, EU;Judkins, CP;Mast, AE;Miller, AA;Selemidis, S;Sobey, CG

Service type: Not applicable

2008

Chromosoma 2008 Aug;117(4):367-80. Epub 2008 Mar

ZNF397, a new class of interphase to early prophase-specific, SCAN-zinc-finger, mammalian centromere protein.

Bailey, SL;Chang, SC;Choo, KH;Earle, E;Graham, AN;Griffiths, B;Kalitsis, P.;Saffery, R

Service type: Knockout mice

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