2024
Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1.
Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions
Service type: Knockout mice
2024
Development. 2024 Mar 1;151(5):dev202617. doi: 10.1242/dev.202617. Epub 2024 Mar 6.
ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development
Service type: Knockout mice
2024
Hepatology. 2024 Feb 16. doi: 10.1097/HEP.0000000000000782. Online ahead of print.
Stellate cell-specific adhesion molecule protocadherin 7 regulates sinusoidal contraction
Service type: Knockout mice
2024
Am J Physiol Lung Cell Mol Physiol. 2024 Feb 13. doi: 10.1152/ajplung.00383.2023.
Disruption of the SP-A/SP-R210L (Myo18Aα) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation
Service type: Knockout mice
2024
Mucosal Immunol. 2024 Feb 7:S1933-0219(24)00007-2. doi: 10.1016/j.mucimm.2024.02.003.
A Trefoil factor 3-Lingo2 axis restrains proliferative expansion of type-1 T helper cells during GI nematode infection
Service type: Knock-in mice
2023
NPJ Parkinsons Dis. 2023 Dec 18;9(1):167. doi: 10.1038/s41531-023-00609-7.
Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice
Service type: Knock-in mice
2023
EMBO Rep. 2023 Nov 14:e57972. doi: 10.15252/embr.202357972. Online ahead of print.
MAPL loss dysregulates bile and liver metabolism in mice
Service type: Knock-in mice
2023
Am J Physiol Gastrointest Liver Physiol. 2023 Nov 14. doi: 10.1152/ajpgi.00140.2023. Online ahead of print.
Defining a timeline of colon pathologies after keratin 8 loss: Rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation
Service type: Knockout mice
2023
Am J Hum Genet. 2023 Nov 3:S0002-9297(23)00358-0. doi: 10.1016/j.ajhg.2023.10.005. Online ahead of print.
Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need
Service type: Knock-in mice
2023
Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2306761120. doi: 10.1073/pnas.2306761120. Epub 2023 Sep 27.
Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation
Service type: Knockout mice