PVG/c

PVG/c

PVG/c

Strain details
Nomenclature PVG/cOzarc
Common namePVG/c
SynonymsPVG
StrainInbred
Coat colourWhite with black hood (a, B, C, h)
SpeciesRat
Genetic background-
LocationArea Oz4

Strain descriptions

  • MHC Haplotype RT1c
  • Animals are docile and has very good breeding performance.
  • Popular inbred for general use as low activity relative to other strains.
  • Resistant to experimental allergic encephalomyelitis and the induction of autoimmune thyroiditis.
  • Useful model for development of autoimmune thyroiditis and diabetes due to insulitis following thymectomy and sublethal x-irradiation.
  • Originally inbred by Glaxo, UK (1946) from stock originating from King College of Household Science to Lister Institute, to Virol to Glaxo (P = Piebald, V = Virol, G = Glaxo, C = ARC Compton where a recognised subline developed). CSIRO from Glaxo, UK.
  • To Murdoch University from John Curtin School of Medical Research, Canberra, Australia as F13+ (1976). JCSMR from CSIRO, NSW Australia as F20 (1970).
  • Animal Resource Centre (ARC), Western Australia received stock strain from Murdoch University, Perth, Australia as F12 (1981). Caesarean derived to SPF status (1981).
  • Strain is transferred to Ozgene ARC in 2023.
  • Application: Useful model for development of autoimmune thyroiditis and diabetes due to insulitis following thymectomy and sublethal x-irradiation.
PVGPVG/cOzarc
WKSMALEFEMALE
326 - 5726 - 50
4
42 - 8525 - 86
565 - 12156 - 96
678 - 15681 - 113
797 - 18599 - 135
8144 - 215109 - 151
9172 - 229124 - 155
10170 - 237120 - 163
11174 - 252133 - 174
12191 - 259148 - 186
13188 - 274148 - 181
14196 - 282146 - 180

Past ARC and transfer reports:

Current Ozgene ARC reports (from 01-Jun-2023)

  • Mouse images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.