Wistar Kyoto

Wistar Kyoto

Wistar Kyoto

Strain details
Nomenclature WKY/NCrlOzarc
Common nameWistar Kyoto
SynonymsWKY
StrainInbred
Coat colourAlbino (a, B, c, hi )
SpeciesRat
LocationArea TBA

Strain descriptions

  • MHC haplotype: RT1l
  • Adult WKY have an inability to excrete acid appropriately after acute or chronic acid loading compared to Sprague Dawley rats.
  • A subset of WKY originating at NIH demonstrates an inheritable transmission of biventricular cardiac hypertrophy (BVH).
  • WKY with BVH provide a natural model of volume load hypertrophy.
  • Recognised normotensive control to use in parallel with studies involving the hypertensive SHR rat.
  • Originally from the outbred Wistar colony at the Kyoto School of Medicine from which the spontaneous hypertensive rat SHR was selected and inbred (note SHR/N). Maintained as a normotensive control to evaluate against the hypertensive SHR strain.
  • NIH received non-inbred Wistar stock from Kyoto School of Medicine, Japan (1971). NIH established the rat as an inbred Wistar colony via brother x sister mating (1971).
  • Flinders University from NIH, USA as F14 (1976).
  • Received to ARC from the School of Medicine, Flinders University, South Australia as F12 (1983). Caesarean derived to SPF status (1983).
  • Wistar Kyoto was transferred from ARC to Ozgene ARC in 2023.
  • Ideal control for the SHR rat
  • ADHD model
Wistar KyotoWKY/NCrlOzarc
WKSMALEFEMALE
332 - 5931 - 51
4
38 - 7945 - 72
567 - 10470 - 92
698 - 14493 - 115
7116 - 183102 - 148
8132 - 216117 - 167
9163 - 243109 - 189
10201 - 270145 - 200
11167 - 292150 - 213
12246 - 303121 - 227
13240 - 309161 - 209
14256 - 309187 - 217

Past ARC and transfer reports:

Current Ozgene ARC reports (from 01-Jun-2023)

  • Rat images are representative only. Actual phenotypes may vary based on genotype, sex, age, husbandry, health status, and other factors.