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Publications

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2021

Eur J Immunol. 2021 Oct 9. doi: 10.1002/eji.202149469. Online ahead of print.

A multifunctional mouse model to study the role of Samd3

Annika E Peters, Konrad Knöpper, Anika Grafen, Wolfgang Kastenmüller

Service type: Knock-in mice

2021

FASEB J. 2021 Oct;35(10):e21940. doi: 10.1096/fj.202100944R.

BHLHE40 promotes macrophage pro-inflammatory gene expression and functions

Atif Zafar, Hang Pong Ng, Gun-Dong Kim, E Ricky Chan, Ganapati H Mahabeleshwar

Service type: Knockout mice

2021

Mol Brain. 2021 Sep 16;14(1):143. doi: 10.1186/s13041-021-00848-w.

Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition

Chelsie A Kadgien, Anusha Kamesh, Austen J Milnerwood

Service type: Knock-in mice

2021

PLoS Biol. 2021 Sep 14;19(9):e3001358. doi: 10.1371/journal.pbio.3001358. eCollection 2021 Sep.

Synthesis of human amyloid restricted to liver results in an Alzheimer disease-like neurodegenerative phenotype

Virginie Lam, Ryusuke Takechi, Mark J Hackett, Roslyn Francis, Michael Bynevelt, Liesl M Celliers, Michael Nesbit, Somayra Mamsa, Frank Arfuso, Sukanya Das, Frank Koentgen, Maree Hagan, Lincoln Codd, Kirsty Richardson, Brenton O'Mara, Rainer K Scharli, Laurence Morandeau, Jonathan Gauntlett, Christopher Leatherday, Jan Boucek, John C L Mamo

Service type: Transgenic mice

2021

Cell Stem Cell. 2021 Aug 27;S1934-5909(21)00341-6. doi: 10.1016/j.stem.2021.08.004. Online ahead of print.

Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

Timothy M Chlon, Emily Stepanchick, Courtney E Hershberger, Noah J Daniels, Kathleen M Hueneman, Ashley Kuenzi Davis, Kwangmin Choi, Yi Zheng, Carmelo Gurnari, Torsten Haferlach, Richard A Padgett, Jaroslaw P Maciejewski, Daniel T Starczynowski

Service type: Knock-in mice

2021

Endocrinology. 2021 Aug 26;bqab179. doi: 10.1210/endocr/bqab179. Online ahead of print.

Cochlear fibrocyte and osteoblast lineages expressing type 2 deiodinase identified with a Dio2 CreERt2 allele

Lily Ng, Ye Liu, Hong Liu, Douglas Forrest

Service type: Knock-in mice

2021

J Neurosci. 2021 Aug 11;41(32):6850-6863. doi: 10.1523/JNEUROSCI.3005-20.2021. Epub 2021 Jul 1.

Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation

C H H Hor, J C W Lo, A L S Cham, W Y Leong, E L K Goh

Service type: Knockout mice

2021

J Immunol. 2021 Aug 1;207(3):902-912. doi: 10.4049/jimmunol.2001251. Epub 2021 Jul 23.

Macrophage-Derived MicroRNA-21 Drives Overwhelming Glycolytic and Inflammatory Response during Sepsis via Repression of the PGE 2/IL-10 Axis

Paulo De Melo, Annie Rocio Pineros Alvarez, Xiang Ye, Amondrea Blackman, Jose Carlos Alves-Filho, Alexandra I Medeiros, Jeffrey Rathmell, Heather Pua, C Henrique Serezani

Service type: Knockout mice

2021

Biochem Biophys Res Commun. 2021 Jul 23;563:66-72. doi: 10.1016/j.bbrc.2021.05.063. Epub 2021 May 29.

Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain

Tomoko Hisaoka, Tadasuke Komori, Kohta Fujimoto, Toshio Kitamura, Yoshihiro Morikawa

Service type: Knock-in mice

2021

Endocrinol Diabetes Metab. 2021 Jun 22;4(3):e00278. doi: 10.1002/edm2.278. eCollection 2021 Jul.

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Aowen Zhuang , Felicia Y T Yap, Danielle J Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A Penfold, Karly C Sourris, Melinda T Coughlan, Benjamin L Schulz, Josephine M Forbes

Service type: Transgenic mice