Publications

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2016

Mol Neurobiol. 2016 Sep;53(7):4874-82. doi: 10.1007/s12035-015-9408-7. Epub 2015 Sep 11.

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome.

E Alcocer-Gómez;C Ulecia-Morón;F Marín-Aguilar;T Rybkina;N Casas-Barquero;J Ruiz-Cabello;B Ryffel;L Apetoh;F Ghiringhelli;P Bullón;JA Sánchez-Alcazar;AM Carrión;MD Cordero

Service type: Knock-in mice

2016

Sci Rep. 2016 Oct 12;6:35160. doi: 10.1038/srep35160.

An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.

G Segerer;K Hadamek;M Zundler;A Fekete;A Seifried;MJ Mueller;F Koentgen;M Gessler;E Jeanclos;A Gohla

Service type: Transgenic mice

2019

Platelets. 2019;30(2):251-255. doi: 10.1080/09537104.2017.1419556. Epub 2017 Dec 29.

Drug-induced immune thrombocytopenia: Mapping of the drug binding site to the membrane-proximal region of platelet GPIX.

Z Ahmadi;J Perdomo;R Wong;BH Chong

Service type: Humanized mice

2018

Nat Commun 2018 Feb 8;9(1):575. doi: 10.1038/s41467-018-03079-1.

SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.

E Mira;L Carmona-Rodríguez;B Pérez-Villamil;J Casas;MJ Fernández-Aceñero;D Martínez-Rey;P Martín-González;I Heras-Murillo;M Paz-Cabezas;M Tardáguila;TD Oury;S Martín-Puig;RA Lacalle;G Fabriás;E Díaz-Rubio;S Mañes

Service type: Transgenic mice

2010

Cell 2010 Aug 6;142(3):456

PNPASE regulates RNA import into mitochondria.

Allen, EL;Chen, HW;Fan, KC;French, SW;Hong, JS;Koehler, CM;Lightowlers, RN;McCaffery, JM;Morse, HC 3rd;Oktay, Y;Smith, GM;Teitell, MA.;Wang, G;Zhang, J

Service type: Knockout mice

2011

IET Syst Biol 2011 May;5(3):174

Exploring phospholipase C-coupled Ca(2+) signalling networks using boolean modelling.

Albert, R;Bhardwaj, G;Patterson, RL.;van, Rossum DB;Wells, CP

Service type: Knockout mice

2015

Nat Med 2015 Aug 17. doi: 10.1038/nm.3924. [Epub ahead of print]

APP intracellular domain-WAVE1 pathway reduces amyloid-β production.

I Ceglia;C Reitz;J Gresack;JH Ahn;V Bustos;M Bleck;X Zhang;G Martin;SM Simon;AC Nairn;P Greengard;Y Kim

Service type: Knockout mice

2019

Nat Immunol. 2019 Aug;20(8):1012-1022. doi: 10.1038/s41590-019-0417-y.

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.

I Mattiola;F Tomay;M De Pizzol;R Silva-Gomes;B Savino;T Gulic;A Doni;S Lonardi;M Astrid Boutet;A Nerviani;R Carriero;M Molgora;M Stravalaci;D Morone;IN Shalova;Y Lee;SK Biswas;G Mantovani;M Sironi;C Pitzalis;W Vermi;B Bottazzi;A Mantovani;M Locati

Service type: Knockout mice

2020

Nature. 2020 Dec 16. doi: 10.1038/s41586-020-03047-0. Online ahead of print.

Antidepressant actions of ketamine engage cell-specific translation via eIF4E

A Aguilar-Valles;D De Gregorio;E Matta-Camacho;MJ Eslamizade;A Khlaifia;A Skaleka;M Lopez-Canul;A Torres-Berrio;S Bermudez;GM Rurak;S Simard;N Salmaso;G Gobbi;JC Lacaille;N Sonenberg

Service type: Knockout mice

2022

Mol Cell. 2022 Jun 16;S1097-2765(22)00540-8. doi: 10.1016/j.molcel.2022.06.004. Online ahead of print.

Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1

Samuel A Killackey, Yuntian Bi, Fraser Soares, Ikram Hammi, Nathaniel J Winsor, Ali A Abdul-Sater, Dana J Philpott, Damien Arnoult, Stephen E Girardin

Service type: Knockout mice