Humanized Models

GENETICALLY MODIFIED MICE FOR RESEARCH

Humanized models
in fastest times

  • Human genomic replacement of any size gene
  • Fastest industry timelines enabled by our goGermline™
    award winning technology
  • Total lowest cost
  • Real-time project status portal and notifications
  • Own your IP, customised mouse models and all the reagents

Get a quote from us.

Please enable JavaScript in your browser to complete this form.

By submitting this form you consent to our team contacting you with the details provided.

GENETICALLY MODIFIED MICE FOR RESEARCH

Humanized models in
fastest times

  • Human genomic replacement of any size gene
  • Fastest industry timelines enabled by our goGermline™
    award winning technology
  • Total lowest cost
  • Real-time project status portal and notifications
  • Own your IP, customised mouse models and all the reagents

Get a quote from us.

Please enable JavaScript in your browser to complete this form.

By submitting this form you consent to our team contacting you with the details provided.

icon

+500
publications

icon

+2k
projects

icon

+30 years of
knowledge

icon

+NYSE, NASDAQ
listed partners

icon

+Top tier academic
partners

icon

+70% repeat
business

NO PROJECT QUEUES WITH goGermline™

How long does it
take to generate
humanized models?

A revolutionary technology for generating gene-targeted humanized mice. Germline transmission is achieved faster and more efficiently with no excess mice, expediting time to first experimental cohorts.

TimeLine
NO PROJECT QUEUES WITH goGermline™

How long does it take to
generate humanized models?

A revolutionary technology for generating gene-targeted humanized mice. Germline transmission is achieved faster and more efficiently with no excess mice, expediting time to first experimental cohorts.

mobileTimeLine
  • Any gene, any size
  • Fastest possible time to first experiment
  • Humanize whole genes
  • Increase germline transmission efficiency
  • Any gene, any size
  • Fastest possible time to first experiment
  • Increase germline transmission efficiency
  • Humanize whole genes
GETTING YOUR PROJECT STARTED

How to get your
humanized
mouse model

Each humanization project is based on your requirements and we will assess your gene of interest to find the most appropriate approach.

  • STEP 1
    Submit your details above
  • STEP 2
    We will reach out for details on your objective
  • STEP 3
    We will provide you a design and quote
GETTING YOUR PROJECT STARTED

How to get your humanized mouse model

Each humanization project is based on your requirements and we will assess your gene of interest to find the most appropriate approach.

  • STEP 1
    Submit your details above
  • STEP 2
    We will reach out for details on your objective
  • STEP 3
    We will provide you a design and quote
FAQ

Questions?

  • We have no project queues.
  • Ozgene’s highly efficient project pipeline allows us to start projects without lengthy waiting periods.
  • Your project will start as soon as Ozgene receives a signed contract and a purchase order.
  • Get starting by requesting a free quote!
  • Ozgene generates mouse models via gene targeting in ES cells using our proprietary goGermline™ technology, which vastly improves the 3R efficiencies and the timeline for development of gene targeted mouse models.
  • We also use various technologies to validate and phenotype your mouse lines e.g. RT-qPCR, Western Blot, ELISA and flow cytometry.
  • Ozgene is able to create large, gene-targeted replacement models. This system enables routine generation of mouse models with very large genomic replacements.

Ozgene offers gene targeting on the following backgrounds:

  • C57BL/6J
  • C57BL/6N
  • BALB/c
  • FVB/n
  • NOD
  • Less common strains as required

We generate genetically engineered humanized models where the human gene replaces the mouse gene, for example

  • humanizing point mutations,
  • humanizing domains, such as extracellular domains,
  • humanizing the entire gene,
  • humanizing multi-gene loci.
ACCREDITATIONS

AAALAC-accredited U.S. facility
SPF testing to FELASA standards